Bromelain's Neuroprotective and Anti-Inflammatory Mechanisms:

Pineapple has bromelain, a mixture of proteolytic enzymes, has demonstrated potent anti-inflammatory effects by modulating key pathways such as the arachidonate cascade and inhibiting pro-inflammatory cytokines. These actions help reduce neuroinflammation, a critical factor in brain aging and neurodegenerative conditions like Alzheimer’s.

Combatting Oxidative Stress:

Pineapple is rich in antioxidants such as vitamin C, polyphenols, and flavonoids, which scavenge free radicals and prevent oxidative stress. This oxidative damage is a key contributor to cognitive decline, and pineapple’s antioxidant properties can help protect neurons from cellular damage, promoting healthier brain aging.

Preventing Cognitive Decline and Neurodegeneration:

Bromelain and other compounds in pineapple, such as phenolic acids, contribute to reducing amyloid plaque formation and tau phosphorylation—hallmarks of Alzheimer’s disease. These mechanisms may help slow the progression of neurodegenerative diseases by promoting neuronal health and reducing protein misfolding.

Functional Food:

Given its rich nutritional profile and neuroprotective properties, pineapple can be considered a valuable functional food for brain health, especially in aging populations. The bioactive compounds present in pineapple have minimal side effects and could play a significant role in enhancing cognitive function and preventing age-related brain disorders.

Medicinal and Nutritional Characteristics of Pineapple in Human Health: A Review (2024)

Bromelain, a Group of Pineapple Proteolytic Complex Enzymes (Ananas comosus) and Their Possible Therapeutic and Clinical Effects. A Summary (2021)

Nutritional Value and Medicinal Benefits of Pineapple (2015)

coming soon